Detection of a single isolate of CTX-M-1-producing Escherichia coli from healthy pigs in Denmark.

1. Kotra LP, Haddad J, Mobashery S. Aminoglycosides: perspectives on mechanisms of action and resistance and strategies to counter resistance. Antimicrob Agents Chemother 2000; 44: 3249–56. 2. Doi Y, Arakawa Y. 16S ribosomal RNA methylation: emerging resistance mechanism against aminoglycosides. Clin Infect Dis 2007; 45: 88–94. 3. Wachino J, Shibayama K, Kurokawa H et al. Novel plasmidmediated 16S rRNA mA1408 methyltransferase, NpmA, found in a clinically isolated Escherichia coli strain resistant to structurally diverse aminoglycosides. Antimicrob Agents Chemother 2007; 51: 4401–9. 4. Doi Y, de Oliveira Garcia D, Adams J et al. Coproduction of novel 16S rRNA methylase RmtD and metallo-b-lactamase SPM-1 in a panresistant Pseudomonas aeruginosa isolate from Brazil. Antimicrob Agents Chemother 2007; 51: 852–6. 5. Doi Y, Ghilardi AC, Adams J et al. High prevalence of metallo-b-lactamase and 16S rRNA methylase coproduction among imipenem-resistant Pseudomonas aeruginosa isolates in Brazil. Antimicrob Agents Chemother 2007; 51: 3388–90. 6. Fritsche TR, Miller GH, Jones RN et al. Detection of methyltransferases (MT) conferring high-level resistance (R) to aminoglycosides (AG) in Enterobacteriaceae (ENT) from Europe, North America and Latin America. In: Abstracts of the Forty-seventh Interscience Conference on Antimicrobial Agents and Chemotherapy, Chicago, IL, 2007. Abstract C2-2053, p. 148. American Society for Microbiology, Washington, DC, USA.